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br Materials Methods br Results
2018-10-30
Materials & Methods Results Discussion To test the role of the Mbnl family of proteins in skeletal muscle function we have developed and examined transgenic mouse strains that show single and combinatorial deficits in the three muscleblind proteins, Mbnl1, Mbnl2 and Mbnl3. In contrast with
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Recent studies showed that endothelium injury is common for
2018-10-30
Recent studies showed that endothelium injury is common for HF onset and development beyond etiology (Fujisue et al., 2015). Endothelial dysfunction closely associates with activation and/or apoptosis of endothelial O4I1 cost lead to release of newly detectable circulating biomarkers related to end
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Standard echocardiography contributes to refinement of strok
2018-10-30
Standard echocardiography contributes to refinement of stroke risk stratification. Moderate–severe LV dysfunction from 2-D echocardiography was the strongest independent predictor of later thromboembolism (The Stroke Prevention in Atrial Fibrillation Investigators, 1992). LV hypertrophy, defined as
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Androgen signaling is central to prostate cancer development
2018-10-30
Androgen signaling is central to prostate cancer development and progression. A milestone in progression of advanced prostate cancer when it transitions from endocrine-driven to paracrine- or intracrine-driven androgen signaling, with progressive complexities in steroid hormone biosynthesis and alte
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Barry and colleagues have successfully used sophisticated an
2018-10-30
Barry and colleagues have successfully used sophisticated and demanding in vivo recording techniques to correlate behavior and TW-37 function at the mesoscale level. This is but one example of the power of those techniques that attempt the difficult task of bridging the behavior of single cells with
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Remarkable progress has been made in
2018-10-30
Remarkable progress has been made in the treatment of ALL. Currently, the five-year overall survival rates exceed 85% in pediatric patients in developed countries (Pui et al., 2015), but remain less than 45% in adults (Jabbour et al., 2015; Bassan and Hoelzer, 2011).The poor outcome in adults has be
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Our previous study demonstrated that
2018-10-30
Our previous study demonstrated that HDAC inhibition contributed to the anticancer effect of statins (Lin et al., 2008). Combining anti-cancer drugs with different mechanisms is a rational approach to improve efficacy. JMF3086, synthesized to inhibit both HDACs and HMGR, exhibits significant benefit
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br Acknowledgements br Value of the
2018-10-29
Acknowledgements Value of the data We provide a standard proteomic dataset based on a highly complex sample (yeast lysate) spiked with different levels of a second calibrated protein mixture of medium complexity (UPS1 standard, 48 proteins), that can be used to statistically evaluate label-fre
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br Specifications Table br Data br Experimental design
2018-10-29
Specifications Table Data Experimental design, materials and methods Acknowledgements T.S.S. is grateful to Nadathur Estates for their support of all the breast cancer research activities at SJRI since 2008. We thank the Department of Biotechnology for the DBT-BBI grant (No: BT/PR13926/M
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br Data The data provided in this
2018-10-29
Data The data provided in this data article compliment the original research article that described the transformation of two subcutaneous implantable cardioverter defibrillator vectors into an 8-lead surface ECG. Fig. 1 illustrate the location of the electrodes on the precordium used during data
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br Acknowledgements br Data This
2018-10-29
Acknowledgements Data This data set contains 5 tables and 1 figure. Tables 1–3 represent the performance of R. maritima in saline wastewater treatment. Tables 4 and 5 show the specific growth rate and the nutrient uptake rate during the study, respectively. The photo of R. maritima plant is pr
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br Introduction Even before the earliest conceptions of
2018-10-29
Introduction Even before the earliest conceptions of a juvenile justice system, adolescents and young adults have presented unique challenges to policy-makers (Steinberg, 2009). Higher incidents of criminal activity, substance use disorders, and the emergence of psychopathologies are often report
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The rs fMRI reflects the stability and integrity of connecti
2018-10-29
The rs-fMRI reflects the stability and integrity of connections in functional networks (Cole et al., 2010). Across development and into adulthood, negative connectivity increases as neural networks become more specialized and as the influence of top-down regulatory networks become more mature and ga
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In PS in vivo data showed an
2018-10-29
In PS, in vivo data showed an increase of the gene expression profile of visfatin, and in vitro data showed a visfatin enhanced tumor necrosis factor-α-induced CXC chemokine ligands 8 and 10 as well as CC chemokine ligand 20 secretions and mRNA expression in human keratinocytes. Thus, visfatin may b
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El presente estudio cr tico tiene como
2018-10-29
El presente estudio crítico tiene como objetivo entonces tomar como punto de partida la publicación en castellano del libro de una de sus teóricas más relevantes para así evaluar los alcances y paradojas de una tradición que ha llegado para enriquecer más de un debate. Se trata de de Lauren Berlant
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