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Kearney and Levine present a detailed survey of teenage
2018-10-23
Kearney and Levine (2012) present a detailed survey of teenage childbearing in the US. The main conclusion is that both actual and perceived lack of economic opportunities influence early motherhood. After these factors have been taken into account, teenage motherhood does not appear to cause additi
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Currently there are no medications or modalities to reduce
2018-10-23
Currently, there are no medications or modalities to reduce both visceral adiposity as well as chronic inflammation in MS or T2DM subjects. Recently, we (Morino et al., 2008a; Adachi et al., 2010) and others (Chung et al., 2008; Gupte et al., 2009) have shown that the beneficial metabolic advantages
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br Funding This work was supported by the
2018-10-23
Funding This work was supported by the NSF fellowshipDGE0909667 (P.J.H.) and the NIH fellowshipDA 035535 (P.J.H.), NIH grants DA038058 and DA012408 (A.G. & U.G.) as well as by the Danish Council for Independent Research Medical Sciences) (U.G.). N.G.C. was supported by the Training Program in I
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Our study reveals additional aspects of
2018-10-23
Our study reveals additional aspects of innate pre-conditioning and pitavastatin in neutrophils. Neutrophil is a key innate leukocyte, and its modulation bears critical relevance to the outcome of sepsis (Stearns-Kurosawa et al., 2011). Neutrophils have multiple functions that include cytokine expre
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br Materials and Methods br Results
2018-10-23
Materials and Methods Results Discussion In this study, we examined the cancer genomes of HPR NSCLCs to identify the genomic mutation profile associated with prolonged exposure to smoky coal pollutants. Of the 14 WGS patients, there was a mean of 12.75somaticgenomicmutations/Mb, 8.16exonicm
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br Materials and Methods br Results br Discussion
2018-10-23
Materials and Methods Results Discussion In this study, we identified several key developmental and stem cell regulatory genes as potential biomarkers of arsenic exposure in the fetal placenta. Our results also revealed extensive sexual dimorphism in the associations between placental gene
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The important concept of crowdsourcing has been taken up
2018-10-23
The important concept of crowdsourcing has been taken up for market-based prediction markets, which operate with the additional benefit of a crowd-generated feedback signal or price, rather than a simple average. Evidence is mounting that prediction markets outperform not only the judgements of indi
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Increasing globalization in travel and trade
2018-10-23
Increasing globalization in travel and trade will intensify the importation of dengue viruses and the potential for further introduction of Ae. aegypti (Gubler and Clark, 1995). If such introductions coincide with suitable vectorial capacity, those cities at the time intervals identified in this stu
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Dengue is a climate sensitive mosquito borne viral disease
2018-10-23
Dengue is a climate sensitive mosquito-borne viral disease that is generally found in the tropics and subtropics (Murray et al., 2013). According to the World Health Organization (World Health Organization (WHO), 2012) and recent assessment on global burden of diseases (GBD2013) (Murray et al., 2015
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br Methods We searched PubMed and Medline
2018-10-23
Methods We searched PubMed and Medline for papers on revaccination with BCG, MV, OPV and smallpox vaccine and mortality/death. The literature searches are explained in Supplementary Figs. 1–4. WHO recently organised a major review of the potential nonspecific effects of BCG purchase OG-L002 and M
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HEV may also contribute to various extrahepatic manifestatio
2018-10-23
HEV may also contribute to various extrahepatic manifestations, including pancreatitis, hematological disorders (thrombocytopenia and anemia), kidney disorders and neurological complications (Guillain-Barré syndrome and meningoencephalitis) (Singh and Gangappa, 2007; Thapa et al., 2009; Wedemeyer et
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B cell activation including the
2018-10-23
B cell activation, including the activation of pre-existing memory B cells (MBC), contributes to a substantial plasmablast response during acute heterologous infection [7–9], resulting in a high increase in neutralizing antibody titers [10] that contribute to temporary cross-protection against all f
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Recently we focused our research on a different aspect of
2018-10-23
Recently, we focused our research on a different aspect of immune function, at the intersection of immunity and genetics, namely on the Human Leukocyte Antigen (HLA) (Georgopoulos et al., 2015). HLA genes are located in the Major Histocompatibility Complex (MHC) of chromosome 6 and play a central ro
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While Biryukov et al propose that mouse monoclonal antibodie
2018-10-23
While Biryukov et al. propose that mouse monoclonal NSC23766 cost to MSP1-19 augment the enhancement effect of normal sera, the reported effect was only moderate when considering absolute parasitamias, and there appears to be large variability in the effect as seen across experimental replicates (da
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Our observation of no statistically significant
2018-10-23
Our observation of no statistically significant associations between any of the immune responses assayed and acquisition of SI suggests that the protection from superinfection observed in our epidemiologic study of the Mombasa Cohort (Ronen et al., 2013) was not mediated by the humoral immune functi
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