• Macroautophagy is a highly conserved major cytoplasmic degra

  2018-10-25

  

  Macroautophagy is a highly conserved major cytoplasmic degradation pathway of eukaryotic cells, which, in contrast to the ubiquitin–proteasome system, can engulf protein rac inhibitor and organelles in a double-membrane vesicle. This so-called autophagosome fuses with lysosomes in order to degrade i

• To date the recently proposed hypothesis

  2018-10-25

  

  To date, the recently proposed hypothesis deciphering the mode of action of DBS points toward a functional inactivation of neuronal activity in the stimulated area, and an excitation of direct axonal and fiber pathways near the electrodes that would regulate distant structures (Montgomery and Gale,

• br Main Trial br Authors Contributions br

  2018-10-25

  

  Main Trial Authors\' Contributions Role of Funding Source National Institute for Health Research Health Technology Assessment (NIHR HTA) (09/55/52) Programme provided funding for the trial, and monitored and advised on the trial\'s progress. The trial is also supported by service support co

• br Acknowledgements The authors thank Jingxian Fan for assis

  2018-10-25

  

  Acknowledgements The authors thank Jingxian Fan for assistance in data collection. Funding for this project was provided by the NSF SEES#1555582 entitled Sustainable Energy Infrastructure Planning. The authors also thank the Purdue Climate Change Research Center (PCCRC) for providing funding in d

• In addition to these findings in

  2018-10-25

  

  In addition to these findings in adults, there is emerging evidence from developmental fMRI studies demonstrating age-related hemispheric lateralization in the IPS. In a longitudinal fMRI study, Emerson and Cantlon (2014) recently demonstrated developmental differences in right and left IPS activati

• While there are a number of reports

  2018-10-25

  

  While there are a number of reports of enhanced coupling between subcortical and cortical structures in adolescence, there have also been some reports of a decrease in functional coupling between amygdala and orbitofrontal activity in adolescence (Spielberg et al., 2014b). Our framework suggests tha

• br Conflict of interest br Acknowledgments This study was

  2018-10-25

  

  Conflict of interest Acknowledgments This study was funded by the UK Medical Research Council (MRC) (G0802226) and the Behavioural and Clinical Neuroscience Institute (BCNI) at the University of Cambridge (jointly funded by the MRC and Wellcome Trust). Additional support was given by the Natio

• br Plasticity sensitive periods and alternative developmenta

  2018-10-25

  

  Plasticity, sensitive periods and alternative developmental trajectories (Question 4) Although there is currently little direct evidence on this issue for autism, examples where transient adaptations have life-long consequences for calcifediol development are common. For example, disruption to t

• One clear limitation to the

  2018-10-25

  

  One clear limitation to the present study is the sample size. As a result, while conventional thresholds and covariates were used in statistical models to correct for Type I error, there remains a chance for Type II error, or the chance that analyses were underpowered to detect smaller but meaningfu

• br Discussion In Adachi et al described the first case

  2018-10-25

  

  Discussion In 1994, Adachi et al described the first case of BPDCN in a Japanese male with cutaneous CD4+ lymphoma. Since then, Petrella et al and other groups have reported additional cases and re-characterized the immunophenotypic and histological features of BPDCN. The nomenclature of such CD4

• dnmt One unexpected benefit of this analysis was that

  2018-10-25

  

  One unexpected benefit of this analysis was that it dnmt illustrated the precision of the AFVA method to measure projectile orientation. Previously, it was determined that AFVA measurements were within 0.1° of on-board electronic measurements [5], but clearly the data from this test smoothly show f

• Siguiendo un modelo t pico de interiorizaci n Monsiv is

  2018-10-25

  

  Siguiendo un modelo típico de interiorización, Monsiváis piensa las consecuencias como previas PLX 4032 las causas. Si lo que surge de ese estigma triturador es una interiorización de “numerosos elementos de la homofobia” y también una subordinación a lo que llama “dispositivos del prejuicio”, enton

• Al respecto Baudrillard se ala

  2018-10-25

  

  Al respecto, Baudrillard (1969) señala que esta totalidad es de orden moral, porque ahí quedarán materializadas las relaciones personales del grupo que cohabita en ese continente espacio-objetual. Sin embargo, Baudrillard olvida mencionar que estas relaciones son también relaciones de poder, y que l

• Trabajos como el de Chandra

  2018-10-25

  

  Trabajos como el de Chandra Talpade Mohanty (2008) van en esta misma dirección cuando muestran que, desde las posiciones marginales, se pueden interrogar las identidades hegemónicas. Para ella, se puede leer la escala ascendente del privilegio, acceder y hacer visibles los mecanismos del poder GSK11

• iPSC derived iHLCs offer a

  2018-10-24

  

  iPSC-derived iHLCs offer a unique advantage in that they can be generated from any donor, which allows a broad spectrum of the human population to be represented in in vitro drug screens and provides an opportunity to assess donor-specific drug responses in vitro. Recent collaborations between drug

15474 records 1027/1032 page Previous Next First page 上5页 10261027102810291030 下5页 Last page