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Remarkable progress has been made in
2018-10-30
Remarkable progress has been made in the treatment of ALL. Currently, the five-year overall survival rates exceed 85% in pediatric patients in developed countries (Pui et al., 2015), but remain less than 45% in adults (Jabbour et al., 2015; Bassan and Hoelzer, 2011).The poor outcome in adults has be
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Our previous study demonstrated that
2018-10-30
Our previous study demonstrated that HDAC inhibition contributed to the anticancer effect of statins (Lin et al., 2008). Combining anti-cancer drugs with different mechanisms is a rational approach to improve efficacy. JMF3086, synthesized to inhibit both HDACs and HMGR, exhibits significant benefit
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br Acknowledgements br Value of the
2018-10-29
Acknowledgements Value of the data We provide a standard proteomic dataset based on a highly complex sample (yeast lysate) spiked with different levels of a second calibrated protein mixture of medium complexity (UPS1 standard, 48 proteins), that can be used to statistically evaluate label-fre
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br Specifications Table br Data br Experimental design
2018-10-29
Specifications Table Data Experimental design, materials and methods Acknowledgements T.S.S. is grateful to Nadathur Estates for their support of all the breast cancer research activities at SJRI since 2008. We thank the Department of Biotechnology for the DBT-BBI grant (No: BT/PR13926/M
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br Data The data provided in this
2018-10-29
Data The data provided in this data article compliment the original research article that described the transformation of two subcutaneous implantable cardioverter defibrillator vectors into an 8-lead surface ECG. Fig. 1 illustrate the location of the electrodes on the precordium used during data
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br Acknowledgements br Data This
2018-10-29
Acknowledgements Data This data set contains 5 tables and 1 figure. Tables 1–3 represent the performance of R. maritima in saline wastewater treatment. Tables 4 and 5 show the specific growth rate and the nutrient uptake rate during the study, respectively. The photo of R. maritima plant is pr
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br Introduction Even before the earliest conceptions of
2018-10-29
Introduction Even before the earliest conceptions of a juvenile justice system, adolescents and young adults have presented unique challenges to policy-makers (Steinberg, 2009). Higher incidents of criminal activity, substance use disorders, and the emergence of psychopathologies are often report
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The rs fMRI reflects the stability and integrity of connecti
2018-10-29
The rs-fMRI reflects the stability and integrity of connections in functional networks (Cole et al., 2010). Across development and into adulthood, negative connectivity increases as neural networks become more specialized and as the influence of top-down regulatory networks become more mature and ga
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In PS in vivo data showed an
2018-10-29
In PS, in vivo data showed an increase of the gene expression profile of visfatin, and in vitro data showed a visfatin enhanced tumor necrosis factor-α-induced CXC chemokine ligands 8 and 10 as well as CC chemokine ligand 20 secretions and mRNA expression in human keratinocytes. Thus, visfatin may b
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El presente estudio cr tico tiene como
2018-10-29
El presente estudio crítico tiene como objetivo entonces tomar como punto de partida la publicación en castellano del libro de una de sus teóricas más relevantes para así evaluar los alcances y paradojas de una tradición que ha llegado para enriquecer más de un debate. Se trata de de Lauren Berlant
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En efecto siendo esta distinci n jur dica
2018-10-29
En efecto, siendo esta distinción jurídica de esferas la condición sine qua non del proyecto burgués, la sociedad decimonónica occidental en su conjunto se verá sometida a una serie de prácticas que harán visible dicha dicotomía, por lo que su legitimidad, siempre tensionada, no solo quedará sujeta
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The protection of Carrageenan induced paw edema in rat
2018-10-29
The % protection of Carrageenan induced paw edema in rat was treated with phenylbutazone guggulosomes. The rats were treated with optimized formulation F3 of prepared guggulosomes. The controlled and treated rats were observed for 0.5, 1, 2, 3 & 4 h on plethysmometer and anti-inflammatory effect was
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Regarding the temperature perception in the gallery people w
2018-10-29
Regarding the temperature perception in the gallery, people were asked whether they were feeling hot, comfortable, chilly, or uncomfortable. Results show that 86% of the users felt comfortable in the building (Figure 11). In addition, 79% of the respondents pointed out that the conversion strategy u
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For symptomatic appendiceal diverticulitis an appendectomy i
2018-10-29
For symptomatic appendiceal diverticulitis, an appendectomy is the optimal treatment. Regarding whether patients without symptoms require an appendectomy, most surgeons suggest a prophylactic appendectomy because, even in symptomless patients, the risk of perforation and mortality is higher in these
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It has been shown that in several cancers
2018-10-29
It has been shown that, in several cancers, only a minority of the cancer dopamine antagonist drugs are able to initiate the formation of new tumors. These cancer-initiation cells are called CSCs, and in several studies the CD44 adhesion molecule has been demonstrated to be expressed specifically i
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