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TgTCEA from petals TgTCEA and TgTCEB from pollen grains
2019-09-03

TgTCEA from petals (TgTCEA1) and TgTCEB from pollen grains (TgTCEB1) were used throughout the study. The recombinant enzymes were expressed in , and purified as the His-tag-free forms as described previously., Enzyme reactions were performed at 4 mM substrates under the same conditions as described
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LVDP values of at the end of reperfusion L
2019-09-03

LVDP values of ~80% at the end of reperfusion. L-NAME treatment did not modify the contractility detected in ischemic control hearts but annulled the actions of BZ acquiring LVDP values up to 40% (Fig. 4 A). A similar pattern was observed when +dP/dtmax was analysed (Fig. 4 B). LVEDP, as an index o
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DIDS While these previous correlative studies have measured
2019-09-03

While these previous correlative studies have measured tDDR1 protein by IHC, these studies have not considered that pDDR1 could also be an important marker of cancer prognosis. A phosphoproteomic survey of lung cancer tissues did identify pDDR1 as one of the most commonly phosphorylated receptor kin
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Our knowledge of DDR induced signaling pathways is
2019-09-03

Our knowledge of DDR-induced signaling pathways is still fragmentary. In particular, we do not know which signaling effectors interact with the phosphorylated receptors and how different effectors are linked to the control of specific cellular functions. The DDRs are at the interface between RTKs an
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br Acknowledgements The study of RING
2019-09-03

Acknowledgements The study of RING-type E3s continues to grow extremely rapidly. We regret that it was possible to only cite a fraction of the outstanding primary publications in this field. This work was supported by the National Institute of General Medical Sciences grants R01 GM088055 and R01
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br Results br Discussion Previous studies have mapped ABCF
2019-09-03

Results Discussion Previous studies have mapped ABCF1 as a risk factor gene for rheumatoid arthritis and autoimmune pancreatitis (Ota et al., 2007, Richard et al., 1998). Additionally, recent genome-wide association studies have also associated ABCF1 with the risk of gout (Dong et al., 2017)
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br Materials and methods br Results br Discussion
2019-09-02

Materials and methods Results Discussion In the past decade, GWAS have attempted to identify genetic variants that confer risk for many human diseases, whose inherited components remain unexplained (Manolio et al., 2009). In a few cases risk variants identified by GWAS have paved the way fo
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br Methods br Results Our study
2019-09-02

Methods Results Our study focused on consecutive postural adjustments (CPAs) between IS and BS (the shaded areas on Fig. 2); that is to say, the Rx kinetics that occur after the end of an upper limb movement. It was dedicated to examining the main features of CPAs and the influence of movement
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Furthermore certain components in the Melanocyte Growth Medi
2019-09-02

Furthermore, certain components in the Melanocyte Growth Medium seem to influence the response to UV radiation [17]: UV-induced effects on tyrosinase activity were less distinct in melanocytes cultured with phorbol 12-myristate 13-acetate [18], which was also an ingredient in our Melanocyte Growth M
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menin The presence of a vicious
2019-09-02

The presence of a “vicious cycle” established between tumor proliferation and paratumor osteolysis plays a crucial role in the development of primary bone tumors [53]. Cancer cells produce soluble factors that activate directly or indirectly via osteoblasts, osteoclast differentiation and maturation
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The reaction of chitosan with DVS should
2019-09-02

The reaction of chitosan with DVS should take place primarily through a nucleophilic attack of the vinyl sulfone groups to the amino groups in chitosan [39,50], although its hydroxyl groups can also be involved, as it happens when using agarose [35]. These reactions create very stable secondary amin
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This relative lack of ET expression in highly
2019-09-02

This relative lack of ET-1 expression in highly malignant epithelial proton pump inhibitors list could be explained by marked cellular anaplasia and cellular dysfunction; we also suggest that the high levels of VEGF, which have been evidenced in highly malignant mammary tumours (Restucci et al., 200
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Using the juxtarenal PPE the
2019-09-02

Using the juxtarenal PPE, the induction of juxta- and suprarenal aneurysms is described herein (Fig. 3A). The infra-/suprarenal part of the cotransporter can now be investigated separately, taking into account different embryological backgrounds and varying reactivity to differing stimuli (reviewed
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The purpose of this study is to
2019-09-02

The purpose of this study is to investigate KDM1B expression and its functional significance in PC. We used lentivirus-mediated shRNA to down-regulate KDM1B expression in PC cell lines in vitro and detected the changes of cell proliferation and apoptosis. These studies provided a novel insight into
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To be a qualified non
2019-09-02

To be a qualified non-specific CYP inhibitor used as an in vitro or in vivo screening tool to distinguish CYP involvement in the overall metabolism, a complete inhibition of the entire metabolism catalyzed by CYPs in a simple experiment is desired. Based on our results, 100 μM atipamezole can comple
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