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Furthermore several animal studies have demonstrated that th
2018-11-12
Furthermore, several animal studies have demonstrated that the injection of IL-6, tumor necrosis factor (TNF)-α, or lipopolysaccharides (which induce IL-1 and TNF-α synthesis) leads to fatigue, decreased life activity, increased somnolence, anorexia, and social withdrawal. These proinflammatory cyto
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Increased serum levels of triglycerides cholesterol
2018-11-12
Increased serum levels of triglycerides, cholesterol, high density lipoproteins and very low density lipoprotein were observed in Dox alone group which indicated that doxorubicin may interfere with metabolism or biosynthesis of lipid. Similar observations were also reported by [9,31]. Pretreatment o
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Finally the potential contribution of CD b cells to
2018-11-12
Finally, the potential contribution of CD11b+ glycogen synthase kinase to the regenerative microenvironment highlights the experimental challenges in defining the mechanism of lung growth. The distinct transcriptional profiles of the CD11b+ cells, and their migration into different anatomic compart
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The most well studied angiogenic factor that is regulated
2018-11-12
The most well-studied angiogenic factor that is regulated by hypoxia is VEGF; hypoxic induction of an HIF-1-dependent bFGF autocrine loop drives angiogenesis, over-expression of Ang-1 causes a significant increase in HIF-1 stabilization and PDGF-BB participates in an autocrine-paracrine survival pat
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br Materials and methods br Results br Discussion Lrig marks
2018-11-12
Materials and methods Results Discussion Lrig1 marks an intestinal stem cell population, but due to reagent differences, the position of Lrig1 in the intestinal epithelium is unclear. We set out to characterize the differences between two Lrig1 antibodies: one available commercially, anti-L
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br Introduction Currently heart disease is the
2018-11-12
Introduction Currently, heart disease is the leading cause of mortality in the industrialized world, partly due to the inability of the heart to regenerate in adults; and also the dietary and life style changes leading to a marked increase in the incidence of type II diabetes (for review, see Arm
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br Introduction Foundational cell fate reprogramming studies
2018-11-12
Introduction Foundational cell fate reprogramming studies revealed ectopic expression of pluripotency-associated transcription factors (TF) OCT4, SOX2, KLF4, and c-MYC (OSKM) or OCT4, SOX2, NANOG, LIN28 (OSNL) in human fibroblasts (hFibs) cultured in pluripotent supportive conditions was sufficie
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br Introduction During early embryogenesis ectoderm differen
2018-11-12
Introduction During early embryogenesis, ectoderm differentiates into surface ectoderm, neural crest, and neural tube. From the surface ectoderm, oral ectoderm and skin develop [1]. In turn, the oral ectoderm differentiates into the adenohypophysis [2,3], dental epithelia [1], salivary glands [1]
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br Materials and methods br Verification and
2018-11-12
Materials and methods Verification and authentication Karyotyping and PCR-RFLP analysis were performed at Reproductive & Genetic Hospital of CITIC-Xiangya. Twenty metaphase cells were observed and all had a normal karyotype of 46, XX. The results of PCR-RFLP assay confirmed a homozygous deleti
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br Particle motion near the plane of symmetry is usually
2018-11-09
Particle motion near the plane of symmetry is usually studied in so-called paraxial approximation, taking into account terms in till only. It is interesting to carry out a numerical experiment for estimating a real number of terms needed. Analytical calculations may be rather cumbersome, but the
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Rapalink-1 The underlying idea of the tomographic method is
2018-11-09
The underlying idea of the tomographic method is in reconstructing f(x, y), i.e. the density distribution function (or distribution of any other quantity) in the plane [3]. The initial data are sets of Radon images Rφ(s) that are projections of the functions f(x, y) on the set of the corresponding s
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The MnO phase on the surface
2018-11-09
The MnO2 phase on the surface of high-silica samples is characterized by a mesh structure consisting of nanorods about 10–20nm in diameter and 500–700nm in length, chemically cross-linked with the CL surface. The MnO2 phase in low-silica samples consists of oval-shaped particles of 50–100nm, scatter
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We had the opportunity to conduct a quantitative study
2018-11-09
We had the opportunity to conduct a quantitative study of the spiritual health of adolescents through our involvement in the cross-national Health Behaviour in School-aged Children study, or HBSC (Freeman et al., 2011). This longstanding study involves researchers in some 43 countries or regions and
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Given this prior work our study is motivated by the
2018-11-09
Given this calcium ionophore prior work, our study is motivated by the importance of understanding whether the association between number of children and weight gain is most consistent with primarily a biologically programmed process, or whether differences exist across populations. Divergent magnit
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In regards to the managerial
2018-11-09
In regards to the managerial implications of this elastase inhibitor research , we understand that providers of content and services, operators and technology companies must work on triggering companies desire to access the benefits of developing a m-CRM strategy, which would help in the advancement
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